Migraines can be disabling, and we don’t have enough quality treatments that can give relief from migraine pain. Part of the problem, researchers said at the American Association of Pharmaceutical Scientists (AAPS) meeting here in San Diego, is that popping a pill for migraine relief is too slow. A more direct method of delivering medication, they say, is with a nasal spray.
Well, We Know It’s Stable
Researchers believe the key to better migraine relief might be prochlorperazine, a dopamine receptor antagonist that has been shown in trials to provide better pain relief than many competing medications, such as metoclopramide, another dopamine receptor antagonist, and ketorolac, a nonsteroidal anti-inflammatory drug (NSAID). The only problem is, prochlorperazine is currently only available in a pill, which has a delayed effect. People with migraines often can’t wait for migraine relief because of the intensity of the pain.
To overcome this limitation, investigators developed a prochlorperazine nasal spray. Currently, they have shown that the drug remains stable in the spray for about 120 days, which is long enough for it to be an effective remedy.
Unfortunately, they haven’t yet had a chance to determine whether the formulation will be safe and effective, which will start with animal trials in the coming year.
Faster Than the Fastest Treatment
Quick, what’s faster than the fastest treatment? Prevention. Better than relying on an abortive migraine medication, even one sped up dramatically in a nasal spray, is finding a way to prevent migraine headaches in the first place.
That’s where TMJ treatment comes in. Not everyone with migraines has TMJ, but for those that do, TMJ treatment can dramatically reduce the frequency and severity of migraines.
If you are a migraine sufferer who wants to be evaluated for TMJ in San Diego, please call (619) 299-5925 for an appointment with a neuromuscular dentist at Strober Dental today.